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3,4-Dichloromethylphenidate (also known by the incorrectly abbreviated name 3,4-CTMP) is a stimulant substance of the phenidate class. It is a structural analog of methylphenidate (Ritalin). The two substances have similar pharmacological profiles but different subjective effects.

It is approximately seven times more potent than methylphenidate in animal studies[citation needed], but likely has weaker reinforcing effects due to its slower onset of action.[citation needed] According to anecdotal reports, the active dose of 3,4-CTMP is approximately 10 times lower than the dose of methylphenidate to achieve a similar effect. 3,4-CTMP has a duration of 6 to 18 hours rather than the 4 to 6 hour duration found with methylphenidate.

3,4-CTMP has an extremely short history of human recreational use and has yet to be documented being sold on the streets. It is available for sale as grey market research chemical by online vendors.[citation needed]

Due to its potent stimulant effects, habit-forming properties as well as an unknown toxicity profile, it is strongly recommended that one use proper harm reduction practices if using with this substance.
Effect of methylphenidate, 3,4-CTMP and ethylphenidate in the nucleus accumbens (NAc) and bed nucleus of the stria terminalis (BNST) slice. After 3 baseline electrical stimulations (10 pulses at 100 Hz) methylphenidate, 3,4-CTMP or ethylphenidate (EPH) was added at a single concentration (arrow).

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